GEMap Platform

Welcome to GEMap

A comprehensive gene essentiality map for drug discovery

1912

Screen

1135

Cell Line

27

Tissue

20000+

Gene

10472

Drugs in DPP

10862

Drugs in DTI

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Essentiality Exporation based on Dependency

Select DataSet:

Select a gene:

Select a module:

Select a cancer (in Single mode):

Essentiality Exporation based on Expression

DataSet:

Select a gene:

Select a module:

Select a cancer (in Single mode):

Essentiality Exporation based on CNV

DataSet

Select a gene:

Select a module:

Select a cancer (in Single mode):

Essentiality Exporation based on Mutation

DataSet:

Upload genelist:

Gene vaildation

Co-Essentiality Exporation based on Co-Dependency

Select a Dependency gene:

Select another Dependency gene:

Select a module:

Select a cancer (in Single mode):

Co-Essentiality Exporation based on Dependency/Expression

Select a Dependency gene:

Select a Expression gene:

Select a module:

Select a cancer (in Single mode):

Co-Essentiality Exporation based on Dependency/CNV

Select a Dependency gene:

Select a CNV gene:

Select a module:

Select a cancer (in Single mode):

Co-Essentiality Exporation based on Dependency/Mutation

Select a Dependency gene:

Select a Mutation gene:

Select a module:

Select a cancer (in Single mode):

Therapeutic Targets Exploration

Select a source:

Select a Gene:

Target include:

Tissue Specificity Exploration

Select Data Type:

Select a targetGene:

Tissue specific

Essentiality for Drug in DPP

Select a gene:

Drug type:

Select a tissue:

Essentiality for Drug in DTI

Select a gene：

Drug type

Download You Way

Select a data type:

Select a data source:

Download by:

Select one or more items:

Visualize You Way

Select a data source:

Upload genelist:

Gene vaildation

Select one or more tissues:

About us

About GEMap

GEMap is a comprehensive platform with the 1912 genome-wide human CRISPR-Cas9 essentiality screens across 1135 human cell lines of 27 cancer types, and 20000+ drug entries from LINCS2020 and DGIdb. GEMap provides a user-friendly interface and a suite of advanced functions to
(1) explore multimodal gene data (Dependency/Expression/CNV/Mutation) across cell lines and tissues;
(2) identify potential therapeutic targets for patients with cancer classified by molecular features, such KRAS mutation
(3) discover tailored treatments and drugs candidate targeting particular genes using large-scale drug perturbation data and drug physical targets.

Feel free to contact us if you have any questions or suggestions about GEMap Platform

Dr.Saisai Tian

📧 saisai_tian@foxmail.com

Ms.Yixue Liang

📧 x15176979013@163.com

Prof.Weidong Zhang

📧 wdzhangy@hotmail.com